GALACTOSYL-INSULIN CONJUGATES USEFUL IN TREATING DIABETICS

摘要

Biologically active gaiactosyl-insulin conjugates useful in the treatment of insulin-dependent diabetics, in particular diabetic humans are disclosed herein. The conjugates comprise at least one D-galactosyl group covalently bonded to insulin. The D-galactosyl group targets the conjugates to the hepatocytes. When these conjugates are administered to the diabetic, a more effective amount of insulin can be delivered to the liver for control of blood glucose levels.