| 摘要 |
A method of selectively assaying for the activity of cathepsin B in mammalian fluids and tissues which may also contain trypsin and trypsin-like enzymes using novel substrates. The substrates are of the general formula: Z - R2 - R1 - X wherein X is an indicator moiety cleavable by cathepsin B, R1 is an amino acid group which is not positively charged, R2 is a hydrophobic amino group, and Z is an amino blocking group. |
