发明名称 REAGENT FOR CLASSIFYING AND IDENTIFYING HUMAN PROSTATE CANCER
摘要 PURPOSE:To classify and identify easily and exactly the prostate cancer from urine and tissue slice by using a reagent contg. the antibody (marked antibody) secreted from the hybridoma (syncytium) of antihuman prostate cancer antibody producing cells and cells which can be subcultured in vitro for a long period of time. CONSTITUTION:The antibody producing cells for a human prostate cancer cell strain 8PC93 are obtd. from the pulpar cells obtd. by immunizing a mouse, etc. with 8PC93. The syncytium of such cells and the myeloma cells, etc. that can be subcultured for a long period of time is obtd. and the antibody secreted from the syncytium is marked with a radioactive material, fluorescent dye, enzyme, etc. The antibody or marked antibody and the urine or tissue slice of a person to be examined are brought into reaction and the activity in marking or the like of the conjugate with the prostate cancer cells is measured. The identification and classification of the prostate cancer cells are thus specifically made possible with high accuracy and the discrimination from the other cancer and tumor is quickly performed.
申请公布号 JPS59188557(A) 申请公布日期 1984.10.25
申请号 JP19830061919 申请日期 1983.04.08
申请人 KUREHA KAGAKU KOGYO KK 发明人 YOSHIMURA MAKOTO;INOGUCHI EIJI;SAITOU KENICHI;KOBAYASHI YASUHIKO;CHIKU TOMOKO;MATSUNAGA KENICHI;FUJII TAKAMI;YOSHIKUMI CHIKAO
分类号 A61K38/00;A61K39/395;C12N15/02;C12P21/08;C12Q1/28;G01N33/574;G01N33/577 主分类号 A61K38/00
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