| 摘要 |
Nicotinoylbenzoguanamines (I; x,y = H or halogen), having an anti- inflammatory action, were prepd. Thus, 2.0 g 2,4-diamino-6p- chlorophenyl-s-triazine was acylated with 2.3 g nicotinic anhydride to give 2.21 g 2,4-bis-nicotinoylamino-6-p-chlorophenyl-s-triazine, which gave 56.8 % inhibition of carrageenin edema in rats at 57.2 mg/ kg i.p.
|
