发明名称 |
KONDENSERADE SJULEMMANDE RINGFOERENINGAR OCH DERAS ANVAEDNING. |
摘要 |
Novel condensed, seven-membered ring compounds of the formula: <IMAGE> [wherein R1 and R2 each represent hydrogen, halogen, trifluoromethyl, lower alkyl or alkoxy, or both jointly form tri- or tetramethylene; R3 is hydrogen, lower alkyl or aralkyl; R4 is hydrogen or alkyl, aralkyl or cycloalkylalkyl which may be substituted; X is a group represented by the formula S(O)n (where n is an integer of 0 to 2); Y is a carboxyl group which may be esterified or amidated; m is 1 or 2] and salts thereof. These compounds exhibit inhibitory activity on angiotensin converting enzyme and so forth, and are of value as an agent for diagnosis, prevention and treatment of hypertension. |
申请公布号 |
FI841590(A) |
申请公布日期 |
1984.10.23 |
申请号 |
FI19840001590 |
申请日期 |
1984.04.19 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
SUGIHARA, HIROSADA;NISHIKAWA, KOHEI;ITO, KATSUMI |
分类号 |
A61K38/00;C07D209/48;C07D281/00;C07D281/10;C07D417/04;C07K5/02;C07K5/06;(IPC1-7):C07D/ |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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