发明名称 Secondary amines, their preparation and use in pharmaceutical compositions
摘要 The compounds of the formula (II): <CHEM> and their pharmaceutically acceptable salts wherein R1 is a hydrogen, fluorine or chlorine atom or a hydroxyl, hydroxymethyl, methyl, methoxy, amino, formamido, acetamido, methylsulphonylamido, nitro, benzyloxy, methylsulphonylmethyl, ureido, trifluoromethyl or p-methoxybenzylamino group; R2 is a hydrogen, fluorine or chlorine atom or a hydroxyl group; R3 is a hydrogen or chlorine atom or a hydroxyl group; R4 is a carboxylic acid group or a salt, ester or amide thereof; R5 is a hydrogen, chlorine or fluorine atom or a methyl, methoxyl or hydroxyl group or a carboxylic acid group or a salt, ester or amide thereof; R6 is a hydrogen atom or a methyl, or propyl group; X is an oxygen atom or a bond; and Y is an alkylene group of up to 6 carbon atoms or a bond have been found to possess anti-obesity and/or antihyperglycaemic activity.
申请公布号 US4478849(A) 申请公布日期 1984.10.23
申请号 US19830474199 申请日期 1983.03.10
申请人 BEECHAM GROUP LIMITED 发明人 AINSWORTH, ANTHONY T.;SMITH, DAVID G.
分类号 A61K31/195;A61K31/205;A61K31/24;A61K31/34;C07C45/28;C07C49/86;C07C65/32;C07C233/00;C07C233/12;C07C275/34;(IPC1-7):A61K31/24;A61K31/19 主分类号 A61K31/195
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