摘要 |
I (R1 = H, halogen, OH, alkyl, alkoxy; X = halo; n = 1,2; R2 = H, Ph, alkoxycarbonyl, alkyl, hexadodesyl, cyclohexyl, α-≮4- (4-chlorobenzeaminoethyl)-phenoxy≉-α-cyclohexylacetoxy-cyclohexy) was prepared from the reaction of II and III. Thus, II was treated with EtONa followed by the addition of α-halogeno-cyclohexylacetic ester to give oxyacetic acid derivatives. The solvents of this reaction can be used non-functional organic solvents, such as dimethylformamido and acetone in a reactive condition.
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