发明名称 |
2,4-DIAMINO-4-SUBSTITUTED PYRIMIDINES |
摘要 |
The pyrimidine derivatives of formula I <IMAGE> I wherein R1 is naphthyl, substituted naphthyl or substituted phenyl; R2 is hydrogen or lower alkoxy; and A is an optionally present ethylene or 1,3-propylene, and wherein the diaminopyridine group has the exo-configuration when A is present, are described. These compounds are useful as antibacterial agents, antimalarial agents and antitumor agents, and can be used in combination with sulfonamides in the control of bacterial infections. |
申请公布号 |
AU2664284(A) |
申请公布日期 |
1984.10.18 |
申请号 |
AU19840026642 |
申请日期 |
1984.04.09 |
申请人 |
HOFFMANN-LA ROCHE, F. + CO. A.G. |
发明人 |
IVAN KOMPIS;RITA LOCHER;HANS MAAG |
分类号 |
A61K31/505;C07D211/70;C07D211/74;C07D211/78;C07D401/04;C07D451/02;C07D451/06;C07D451/14 |
主分类号 |
A61K31/505 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|