METHOD OF DELIVERING DRUG WITH AID OF EFFERVESCENT ACTIVITY GENERATED IN ENVIRONMENT OF USE

摘要

An osmotically driven device for dispensing an active agent into a fluid environment is disclosed, which device comprises a semipermeable wall surrounding and defining an inner compartment containing an active agent having limited solubility in the fluid, an outlet passageway through the wall for connecting the compartment with the exterior of the device for dispensing the active agent, the device characterized in that the compartment contains a basic compound that generates carbon dioxide gas on being dispensed from the compartment, thereby improving the delivery of the active agent from the device.