| 摘要 |
<p>The present invention provides a control or calibration serum, containing at least one compound of the general formula: (I) in which T is a hydrogen atom or a methyl, hydroxymethyl or methoxymethyl - group, X is a hydrogen atom, a hydroxymethyl group or a methyl group , if Y is a hydroxyl group, a hydroxymethyl group or an NR2 group , Y is a hydrogen atom, a hydroxyl group or a hydroxymethyl or NR2 group and Z a hydroxyl group or an -O-CH2-CH2OH group , if Y is a hydrogen atom or a hydroxymethyl group , or a hydroxymethyl group or a carboxyl derivative; or T is an ethyl or isopropyl group , X is a hydrogen atom or a methyl, hydroxymethyl or methoxy group , Y is a hydroxyl group or a hydroxymethyl or NR2 , group and Z is a carboxyl derivative and each R, independently of one another, is a hydrogen atom or an alkyl group containing 1 or 2 carbon atoms and optionally containing a hydroxyl group, and/or at least one compound of the general formula: HO(CH2-CH2-O)nH . (III) in which n is a whole number of from 2 to 8, in an amount which is sufficient wholly or partly to prevent turbidities in reconstituted serum after previous lyophilisation. The present invention also provides a process for the preparation of low turbidity calibration or control sera in which use is made of compounds of general formula I and/or II.</p> |
