发明名称 PROCESS FOR THE PREPARATION OF OCTADECENIC ACID AMIDE
摘要 Title compds. (I; R=alkyl, alkenyl, cycloalkyl, aralkyl, furfuryl, Ph, (CH2)3-X; X=heterocycle; n=0-3), useful as blood platelet aggregation inhibitors, were prepd. by the reaction of II with III. Thus, stirring 1.55g 9,12-dioxo-trans-10-octadecenoic acid with 300mg isoproplamine in chloroform in the presence of 610mg trienthylamine and 760mg isobutylchlorocarboxylic acid gave 1.65g N-isopropyl-9, 12-dioxo-trans-10-octadecenide(93.9% yield).
申请公布号 KR840001669(B1) 申请公布日期 1984.10.13
申请号 KR19800004751 申请日期 1980.12.13
申请人 NIPPON SHINYAKU CO.,LTD. 发明人 MATSUMURA SHINGO;ENOMOTO HIROSHI;MAEHARA MITSUHIRO;HAYASHI HIDEYA;FUJIDA YUKIO;OJAKI MASAKUNI
分类号 C07D295/20;A61K31/16;A61K31/165;A61K31/34;A61K31/341;A61K31/40;A61K31/4015;A61K31/425;A61K31/426;A61K31/44;A61K31/445;A61K31/535;A61K31/5375;A61P7/02;A61P35/00;C07C67/00;C07C231/00;C07C235/76;C07D207/09;C07D207/27;C07D211/56;C07D277/20;C07D277/46;C07D295/12;C07D307/52;(IPC1-7):C07C103/58 主分类号 C07D295/20
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