摘要 |
<p>A diagnostic preparation useful in a method of diagnosis using NMR, X-ray and ultra-sound, comprises (i) a physiologically tolerable complex salt which contains (a) a central element selected from elements having atomic numbers of from 21 to 29, 42, 44 and from 57 to 83, and (b) a radical of a physiologically-tolerable complex-forming acid and, if desired, (c) a radial selected from radicals of inorganic and organic bases and amino acids, and (ii) a physiologically tolerable carrier.The salts are claimed perse and may contain e.g. methylenephosphonic acid or aminoacetic acid type complexing acids. Metal complexes of monoclonal antibodies coupled with DTPA and CDTA are also prepared (Example 55).</p> |