1-N-(.alpha.-HYDROXY-.omega.-AMINOALKANOYL) DERIVATIVES OF 5, 3',4'-TRIDEOXY- OR 5,3',4'-TRIDEOXY-6'-N-METHYL- OR 5,3',4',6-TETRADEOXY-KANAMYCIN B AND PRODUCTION THEREOF

摘要

New 1-N-(.alpha.-hydroxy-.omega.-aminoalkanoyl) derivatives of 5,3',4'-trideoxy- or 5,3',4'-trideoxy-6'-N-methyl-or 5,3',4',6"-tetradeoxy-kanamycin B and production thereof New antibacterial compounds are provided, including a 1-N-(.alpha.-hydroxy-.omega.-aminoalkanoyl)-5,3',4'-trideoxykanamycin B; a 1-N-(.alpha.-hydroxy-.omega.-aminoalkanoyl)-5,3',4',6"-tetra-deoxykanamycin B; and a 1-N-(a-hydroxy-.omega.-aminoalkanoyl)-5,3',4'-trideoxy-6'-N-methylkanamycin B; as well as 5,3',4',6"-tetradeoxykanamycin B and 5,3',4'-trideoxy-6'-N-methylkanamycin B.