| 发明名称 |
PHARMACOLOGICALLY ACTIVE 4-(2-HYDROXY-4-(SUBSTITUTED)PHENYL)NAPHTHALEN-2(1H)-ONES AND 2-OIS |
| 摘要 |
Compounds having the formula <IMAGE> wherein <IMAGE> <IMAGE> <IMAGE> <IMAGE> <IMAGE> R1 is hydrogen, benzyl or alkanoyl, X is C2-4 alkylene; and Z-W is alkyl, phenylalkyl or pyridylalkyl which can have an oxygen atom as part of the alkyl chain and their use as CNS agents, antidiarrheals and antiemetics. Processes for their preparation and intermediates therefor are described. |
| 申请公布号 |
PH17616(A) |
申请公布日期 |
1984.10.05 |
| 申请号 |
PH19200000262 |
申请日期 |
1981.09.17 |
| 申请人 |
PFIZER INC. |
发明人 |
MICHAEL ROSS JOHNSON;LAWRENCE SHERMAN MELVIN, JR. |
| 分类号 |
C07D295/08;A61K31/00;A61K31/045;A61K31/05;A61K31/085;A61K31/12;A61K31/335;A61K31/357;A61P1/00;A61P25/00;A61P25/04;C07C27/00;C07C39/17;C07C39/23;C07C39/42;C07C41/00;C07C43/196;C07C43/20;C07C43/23;C07C45/00;C07C45/59;C07C45/67;C07C45/69;C07C49/623;C07C49/747;C07C49/753;C07C62/38;C07C67/00;C07C69/035;C07C69/353;C07C229/06;C07D295/14;C07D295/15;C07D317/00;C07D317/72;C07D319/00;C07D319/08;C07D321/00;C07D321/10;C07D405/04;C07D493/06;C07D493/10;C07F9/12 |
主分类号 |
C07D295/08 |
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