| 摘要 |
NEW MATERIAL:A compound shown by the formula I [R<1> is H, lower akyl, lower alkoxy (carbonylmethyl), etc.; R<2>-R<4> are H, halogen, lower alkyl, lower alkoxy, nitro, OH, etc.; A is -CO-, or -CH(OH)-; Z is H, lower alkoxy, or lower alkyl] and acid addition salt. EXAMPLE:2-Isopropyl-3-(p-nitrobenzoyl)pyrazole[1,5-a]pyridine. USE:An inhibitor of blood platelet aggregation. PREPARATION:1mol compound shown by the formula II is reacted with preferably 1-3mol carboxylic acid (reactive derivative) shown by the formula III under heating at 120-160 deg.C, to give a compound wherein the group A of the formula shown by the formula I is -CO-.
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