Tetrahydrothiophenone derivative active in respiratory system affections.

摘要

N-(2-Thenoyl)-N-(2-keto-2,3,4,5-tetrahydro-thio-phene-3-yl)amine of formula I is a valuable bronchosecretogogue, antitussive and antiinflammatory agent. It may be prepared by reacting homocysteine thiolactone hydrochloride with a reactive derivative of 2-thiofenecarboxylic acid. The compound of the invention may be formulated with conventional pharmaceutically acceptable carriers or diluents, to provide pharmaceutical composition.