N-OXACYCLYL-ALKYLPIPERIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL PRODUCTS CONTAINING THEM, AND THEIR USE

摘要

HOE 81/F 145 of the disclosure: Compounds of the formula I (I) in which n denotes one, two or three; p and q denote integers from one to three, (p+q) being the number four; Ph denotes unsubstituted 1,2-phenylene or 1,2-phenylene which carries one to three identical or different and independent substituents, possible substituents being straight-chain or branched alkyl with 1 to 6 carbon atoms, alkoxy with 1 to 4 carbon atoms, alkylenedioxy with 1 or 2 carbon atoms,halogen, trifluoromethyl, nitro or alkanoyl with 1 to 3 carbon atoms; R1 and R2 are identical or different and independent, and denote hydrogen or alkyl with 1 to 5 carbon atoms; R3 and R4 are identical or different and independent, and denote hydrogen or alkyl with 1 to 5 carbon atoms, or R3 and R4 together denote PH' (as defined for Ph) or together denote straight-chain or branched alkylene with 1 to 5 carbon atoms; R5 denotes hydrogen, alkyl with 1 to 5 carbon atoms, or phenyl which is optionally monosubstituted or disubstituted by straightchain or branched alkyl with 1 to 6 carbon atoms, alkoxy with 1 to 4 carbon atoms, alkylenedioxy with 1 or 2 carbon atoms, halogen, trifluoromethyl, nitro or alkanoyl with 1 to 3 carbon atoms; X denotes an oxygen or sulfur atom, imino or alkylimino with 1 to 4 carbon atoms; and Y denotes an oxygen or sulfur atom or a sulfinyl group are described. Processes for the preparation of these compounds are also described. The compounds are useful as medicaments, by antipsychotic actions.