发明名称
摘要 <p>Compounds of formula I <IMAGE> I in which R1 is a heterocyclic ring containing one or more heteroatoms selected from N, O and S; in which R2 is H, a straight or branched chain alkyl group containing 1 to 4 carbon atoms, an alkenyl group containing 3 to 6 carbon atoms, an alkynyl group containing 3 to 6 carbon atoms or a cycloalkyl group containing 3 to 7 carbon atoms; in which R3, is H, a straight chain alkyl group containing 1 to 3 carbon atoms or a formyl group in which R4, R5 and R6 which may be the same or different, are H, halo, trifluoromethyl, hydroxy, an alkyl group containing 1 to 3 carbon atoms, an alkoxy group containing 1 to 3 carbon atoms, phenyl or R4 and R5, together with the carbon atoms to which they are attached, form an optionally substituted second benzene ring; and their pharmaceutically acceptable salts have utility in the treatment of depression. Pharmaceutical compositions and processes for the preparation of compounds of formula I are disclosed.</p>
申请公布号 GR78725(B) 申请公布日期 1984.10.02
申请号 GR19448301725 申请日期 1983.09.27
申请人 THE BOOTS COMPANY PLC 发明人 BERNARD JOHN ARMITAGE;JOHN ROSINDALE HOUSLEY;JAMES EDWARD JEFFERY;DAVID NORMAN JOHNSTON
分类号 C07D257/02;A61K31/135;A61K31/34;A61K31/381;A61K31/385;A61K31/40;A61K31/415;A61K31/4164;A61K31/425;A61K31/44;A61K31/4425;A61P25/24;A61P25/26;C07D207/09;C07D207/12;C07D207/335;C07D213/38;C07D231/12;C07D233/54;C07D233/61;C07D233/64;C07D235/14;C07D249/08;C07D257/04;C07D277/28;C07D295/13;C07D295/15;C07D307/14;C07D307/34;C07D307/52;C07D333/20;C07D333/22;C07D339/08;C07D401/12;C07D409/12;C07D521/00 主分类号 C07D257/02
代理机构 代理人
主权项
地址