| 摘要 |
PURPOSE:To provide an anti-suntan agent containing fine powder of titanium oxide or surface-treated titanium oxide and indomethacin or its salt, and capable of preventing sunburn and the melanization of the skin. CONSTITUTION:The objective anti-suntan agent contains (A) fine poder of titanium oxide and/or surface-treated titanium oxide and (B) indomethacin of formula and/or its salt. The powder (A) has the maximum diameter of <=0.1mu and average diameter of 10-40mmu, and is effective to shield the ultraviolet radiation irradiated to the skin. The inflammation and the melanosis caused by the ultraviolet radiation which is not shielded by the above physical shielding effect and intruding into the skin can be physiologically suppressed and prevented by the indomethacin. Preferable contents of the powder and the indomethacin or its salt in the whole agent are 1.0-20.0wt% and 0.01-5.0wt%, respectively. |
