发明名称 PROCESS FOR MAKING 1-(3-BENZYLOXYPHENYL)-1,1-DIMETHYLHEPTANE AND INTERMEDIATES THEREFOR
摘要 A process for preparing 1-(3-benzyloxyphenyl)-1,1-dimethylheptane by reacting 1-(3-benzyloxyphenyl)-1-chloro-1-methylheptane in a solvent at -50 DEG to 10 DEG C with from 1 to 3 molar equivalents of trimethylaluminum. Also included are the novel intermediates 1-(3-benzyloxyphenyl)-1-chloro-1-methylheptane and 1-(3-benzyloxyphenyl)-1-methylheptan-1-ol and their preparation. The title compound is a valuable intermediate in the synthesis of certain analgesic agents.
申请公布号 DE3260609(D1) 申请公布日期 1984.09.27
申请号 DE19823260609 申请日期 1982.10.27
申请人 PFIZER INC. 发明人 MELVIN, LAWRENCE SHERMAN
分类号 C07C43/263;C07C37/055;C07C39/11;C07C41/00;C07C41/22;C07C41/30;C07C43/205;C07C43/225;C07C43/23;C07C45/69;C07C45/71;C07C67/00;(IPC1-7):C07C43/20;C07C43/22;C07C41/24 主分类号 C07C43/263
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