1,1-DISUBSTITUTED-HEXAHYDRO-INDOLO(2,3-A)QUINOLIZINE DERIVATIVES AND THEIR USE IN THE ENANTIOSELECTIVE SYNTHESIS OF OPTICALLY ACTIVE 14-OXO-E-HOMO-EBURNANE DERIVATIVES

摘要

Compounds of general formula (A),

wherein
R<1> represents a C1-4 alkyl group;
X represents a residue of an acid;
either B represents a group -COOR<2> (in which R<2> represents a C1-4 alkyl group) and Z represents a group

(in which R<3> and R<5>, which may be the same or different, each represents a C1-4 alkyl radical) or B represents a group -COOH or a hydrogen atom and Z represents a group -CH2COOH, of use in the enantioselective synthesis of optically active 14-oxo-E-homo-eburnane derivatives.