Halogenated prostacyclins pharmaceutical use thereof and hydroxy intermediates therefore

摘要

Novel 5- or 7-monohalogenated or 5,7-dihalogenated 6-PGI1 and 5- or 7-monohalogenated or dihalogenated PGI2(except 5-monofluorinated PGI2). The novel halogenated prostacyclins are useful for controlling vascular actions and also in organ transplantation, extra-corporeal circulation and the like. The present invention also provides processes for preparing the novel halogenated prostacyclins.