| 摘要 |
There is presented novel benzophenone derivatives of the formula <IMAGE> I wherein R1 is hydrogen or lower alkyl, R2 is hydrogen or aminoacetyl, R3 is hydrogen or lower alkyl, R4 is hydrogen or halogen, R5 is hydrogen, amino, nitro or a group of the formula R3-ON=C(R6)-and R6 is lower alkyl, with the proviso that R5 is a group of the formula H-ON=C(R6)-when R2 and R3 are both hydrogen, and their pharmaceutically acceptable acid addition salts. The compounds exhibit aldosterone-antagonistic properties and are accordingly suitable for the control or prevention of heart failure, hepatic ascites, primary aldosteronism and idiopathic hypertension.
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