发明名称 |
3,5-Disubstituted-4'-(9-acridinylamino)-methane-sulfon-m-anisidide compounds having antitumor properties |
摘要 |
3,5-Disubstituted-4'-(9-acridinylamino)-methane-sulfon-m-anisidide compounds represented by the general formula <IMAGE> I in which R2 and R3 represent, respectively, -CH3 and -CONHCH3, -CH3 and -CONHCH2CONH2, -Cl and -CONHCH2CONH2, -CONHCH3 and -CH3; and acid addition salts thereof have unexpectedly high antitumor activity in leukemic animals and low or no direct mutagenicity.
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申请公布号 |
US4472582(A) |
申请公布日期 |
1984.09.18 |
申请号 |
US19820386104 |
申请日期 |
1982.06.07 |
申请人 |
DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND |
发明人 |
CAIN, DECEASED, BRUCE F.;ATWELL, GRAHAM J.;BAGULEY, BRUCE C.;DENNY, WILLIAM A. |
分类号 |
A61K31/00;A61P35/00;C07D219/04;C07D219/06;C07D219/10;(IPC1-7):C07D219/08;A61K31/43 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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