| 摘要 |
PURPOSE:To obtain the titled compound useful for synthesizing alkaloid, by condensing an oxime sulfonate with a silyl enol ether in the presence of a reagent. CONSTITUTION:An oxime sulfonate shown by the formula I (R<1> and R<2> are H, or 1-30C hydrocarbon which may contain N, O, P, or S; R<3> is 1-20C hydrocarbon) is condensed with a silyl enol ether shown by the formula II (R<4>-R<6> are H, 1- 30C hydrocarbon which may contain N, O, P, or S; R<7>-R<9> are 1- 20C hydrocarbon) in the presence of a reagent [e.g., RnAlX3-n(R is 1-20C hydrocarbon; X is H, or halogen, etc.; 0<=n<=3)] to give a beta-acylenamine shown by the formula III. A blending ratio of oxime sulfonate, silyl enol ether and the reagent is (1:0.1: 0.1)-(1:5:20), and the condensation reaction is carried out in an inert solvent by taking handling of the reagent into consideration.
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