发明名称 Medicinal and prophylactic dentifrice gel having caries-inhibitory action
摘要 The invention relates to stomatology. The dentifrice gel forming the subject of the invention is of the type containing a gelling substance, a humidifying substance, a surfactant substance, an aromatic and a substance having caries-inhibitory action containing sodium monofluorophosphate, and is characterised in that it contains 1.7 to 11% by weight of a substance having caries-inhibitory action consisting of a mixture of sodium monofluorophosphate with a product obtained by treatment of bone tissue with a dilute inorganic acid until the inorganic constituents and the water-soluble proteins and hydrolysis products thereof contained in the aforementioned bone tissue have been removed completely, by separation of the solution obtained, by its dilution with water with addition of a stabiliser such as citric acid or a salt of the latter, and by subsequent neutralisation of the solution and drying, and containing the following constituents (% by weight): calcium, 2 to 6; sodium, 19 to 23; potassium, 0.04 to 0.18; inorganic acid anion (chloride), 6 to 10.6; orthophosphoric acid anion, 1.5 to 5.0; water-soluble proteins and hydrolysis products thereof, 1.0 to 5.0; magnesium, 0.05 to 0.2; group of trace elements including fluorine, manganese, tin, zinc and iron, 0.01 to 0.02; complex citrate compounds, calculated as citric acid anion, q.s. 100%. The dentifrice in question may be used, in particular, for the daily hygiene of the buccal cavity, as well as to exert an anti-inflammatory action in disorders of the periodontium, and in particular in periodontosis.
申请公布号 FR2542198(A1) 申请公布日期 1984.09.14
申请号 FR19830004073 申请日期 1983.03.11
申请人 RIZHSKY MEDITSINSKY INSTITUT 发明人 G. N. PAKHOMOV, A. Y. LUSTE, A. G. KOLESNIK, V. N. DEMISHEV, E. I. PASHININA, M. V. MORDVINOVA, L. V. MOROZOVA, L. M. BOGINSKAYA, I. B. VOSKRESENSKAYA, S. Z. OSADCHUK ET G. I. KADNIKOVA;LUSTE A Y;KOLESNIK A G;DEMISHEV V N;PASHININA E I;MORDVINOVA M V;MOROZOVA L V;BOGINSKAYA L M;VOSKRESENSKAYA I B;OSADCHUK S Z;KADNIKOVA G I
分类号 A61K6/00;A61K8/73;A61K8/81;A61K8/98;A61K35/32;A61Q11/00;(IPC1-7):A61K35/32;A61K7/26 主分类号 A61K6/00
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