发明名称 PREPARATION OF WATER-BASED ENTERIC COATING LIQUID
摘要 PURPOSE:To prepare the titled coating liquid easily and economically, by dispersing a water-based gel of a carboxyalkyl cellulose ester derivative in water or in an aqueous solution of an alcohol. CONSTITUTION:The objective water-based enteric coating liquid having a solid concentration of >=10wt% and an extremely excellent film-forming property represented by the minimum film-forming temperature of <=40 deg.C, in some cases <=25 deg.C, can be prepared by dispersing (A) a water-based gel of a carboxyalkylcellulose ether derivative of formula (Gul is anhydrous glucose unit skeleton of a cellulose of formula C6H7O2; n is 1-5; R is methoxy, ethoxy or OH) and having a water-content of 30-70wt%, preferably 40-60wt% (wet-basis) in (B) water or an aqueous solution of an alcohol containing <=20wt% of a 1-3C lower alcohol. Addition of a small amount of alcohol is extremely effective to improve the film-forming property, eliminate the foams of the dispersion, or prevent the proliferation of bacterial cells during the storage of the dispersion.
申请公布号 JPS59157032(A) 申请公布日期 1984.09.06
申请号 JP19830029262 申请日期 1983.02.25
申请人 KOJIN KK 发明人 MUKOUYAMA HIDEAKI;NAGATSU YOSHIROU;HIRAOKA RIYOUICHI;SAITOU MOTOYASU
分类号 A61K9/36;A61K9/62;A61K47/00;A61K47/38 主分类号 A61K9/36
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