摘要 |
Compounds of formula (I): <CHEM> and salts thereof: wherein R<1> is hydrogen or methyl; R<2> is hydrogen or methyl; R<3> is phenyl optionally substituted with one or two of the following; fluorine, chlorine, bromine, trifluoromethyl or C1-6 alkyl; or is benzofuran-2-yl; n is 1 or 2; X is C1-15 straight or branched alkylene. A<1> is hydrogen, C1-6 alkyl, or optionally substituted benzyl A<2> is hydrogen, C1-6 alkyl, or optionally substituted benzyl, and E is hydrogen, halogen, C1-6 alkoxy, C1-6 alkyl; or mono- or di-C1-6 alkylamino, are useful in treating obesity, hyperglycaemia or inflammation, or inhibiting platelet aggregation. |