发明名称 SECONDARY AMINES, THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE
摘要 Compounds of formula (I): <CHEM> and salts thereof: wherein R<1> is hydrogen or methyl; R<2> is hydrogen or methyl; R<3> is phenyl optionally substituted with one or two of the following; fluorine, chlorine, bromine, trifluoromethyl or C1-6 alkyl; or is benzofuran-2-yl; n is 1 or 2; X is C1-15 straight or branched alkylene. A<1> is hydrogen, C1-6 alkyl, or optionally substituted benzyl A<2> is hydrogen, C1-6 alkyl, or optionally substituted benzyl, and E is hydrogen, halogen, C1-6 alkoxy, C1-6 alkyl; or mono- or di-C1-6 alkylamino, are useful in treating obesity, hyperglycaemia or inflammation, or inhibiting platelet aggregation.
申请公布号 DE3260490(D1) 申请公布日期 1984.09.06
申请号 DE19823260490 申请日期 1982.03.26
申请人 BEECHAM GROUP PLC 发明人 SMITH, DAVID GLYNN
分类号 C07D307/81;(IPC1-7):C07C91/16;A61K31/13;A61K31/34 主分类号 C07D307/81
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