摘要 |
PURPOSE:To selectively adsorb and remove lipoprotein, by immobilizing a polyanion compound by an inorg. porous substance with an average pore size of 700-4,000Angstrom . CONSTITUTION:A polyanion compound having affinity to lipoprotein such as heparin, dextrane sulfate, chondroitin sulfate, chondroitin polysulfate, heparanic acid or keratanic acid is immobilized by an inorg. porous substance having an averate pore size of 700-4,000Angstrom , a void volume of 20% and a specific surface area of 3m<2>/g or more such as silica gel, alumina, porous glass, silica-alumina, hydroxyapatite or calcium silicate according to a physical adsorbing method, an ion bonding method or a covalent bonding method. The amount polyanion compound to be immobilized is pref. 0.5-20mg per milli-liter of a column volume.
|