发明名称 PREPARATION OF ERYTHROPOIETIN
摘要 PURPOSE:To obtain erythropoietin(EPO for short), a factor for promoting formation of erythrocyte and a drug applicable to patients of anemia, patients after operations, etc. in high purity in high yield, by bringing a substance containing EPO to an adsorbent to which an immune antibody is bonded. CONSTITUTION:A substance (e.g., urine of normal human or patient of anemia, or a treated material thereof) containing EPO is brought into contact with an adsorbent to which a monoclonal anti EPO antibody obtained from hybridoma cell prepared from cell fusion of a splenic cell of experimental animal immunized with EPO and a myeloma cell is bonded, EPO is adsorbed on it, and eluted to give the desired EPO.
申请公布号 JPS59155395(A) 申请公布日期 1984.09.04
申请号 JP19830026399 申请日期 1983.02.21
申请人 YUKIJIRUSHI NIYUUGIYOU KK 发明人 CHIBA HIDEO;SASAKI RIYUUZOU;UEDA MASAJI
分类号 C12N15/02;C07G15/00;C07K1/14;C07K1/22;C07K14/00;C07K14/505;C07K14/52;C07K16/00;C07K16/22;C12N5/00;C12N15/00;C12P21/00;C12P21/08 主分类号 C12N15/02
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