发明名称 Benzodiazepine derivatives.
摘要 <p>Benzodiazepine derivatives represented by the following general formula or pharmaceutically acceptable salts thereof: &lt;Chemistry id="chema01" num="0001"&gt;&lt;Image id="ia01" he="26" wi="59" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /&gt;&lt;/Chemistry&gt;wherein &lt;UnorderedLists id="ula01" listStyle="none"&gt;&lt;ListItem&gt;R&lt;Sup&gt;1&lt;/Sup&gt; is -COR&lt;Sup&gt;4&lt;/Sup&gt; (R&lt;Sup&gt;4&lt;/Sup&gt; is a carboxylic acid residue) or an alkyl or aralkyl group (these groups have a substituent selected from a carboxyl group, an amino group and a cyano group), R&lt;Sup&gt;2&lt;/Sup&gt; is a lower alkyl group and R&lt;Sup&gt;3&lt;/Sup&gt; is a hydrogen atom or a lower alkyl group.&lt;/ListItem&gt;&lt;/UnorderedLists&gt;</p><p>The above compounds are low in toxicity and have antitumor activity.</p>
申请公布号 EP0116911(A1) 申请公布日期 1984.08.29
申请号 EP19840101345 申请日期 1984.02.09
申请人 GREEN CROSS CORPORATION 发明人 UEDA, YASUO;SHIRAGA, YUSEI;MORIMOTO, SATOSHI;KAGITANI, YOSHIO;FUNAKOSHI, SATOSHI;SUYAMA, TADAKAZU
分类号 C07D487/04;(IPC1-7):07D487/04;61K31/55 主分类号 C07D487/04
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