摘要 |
<p>Compounds having general formula I
<Chemistry id="chema01" num="0001"><Image id="ia01" he="34" wi="96" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>wherein
<UnorderedLists id="ula01" listStyle="none"><ListItem>R<Sub>1</Sub> is hydrogen, lower alkyl, lower alkoxy, alkylenoxy, halogen, cyano, carboxyamido or ureido group optionally separated from the phenyl ring by a methylene or ethylene bridge;</ListItem><ListItem>R<Sub>2</Sub> is hydrogen, halogen, lower alkyl or alkoxy;</ListItem><ListItem>R<Sub>3</Sub> is hydrogen, halogen, lower alkyl, lower alkoxy or R<Sub>2</Sub> and R<Sub>3</Sub>, taken together, are a methylendioxy group;</ListItem><ListItem>R<Sub>4</Sub> is hydrogen or lower alkyl, endowed with remarkable cardioselective β-adrenolytic properties, are described.</ListItem></UnorderedLists></p><p>The process for their preparation and pharmaceutical compositions containing them are also described.</p> |