发明名称 Esters of phosphinylalkanoyl substituted prolines
摘要 Hypotensive activity is exhibited by compounds having the formula <IMAGE> and salts thereof wherein R1 is alkyl, aryl, arylalkyl, cycloalkyl, or cycloalkylalkyl; R2 is cycloalkyl, 3-cyclohexenyl or 2-alkyl-3-cyclohexenyl; R3 is alkyl, cycloalkyl, phenyl or alkoxy; R4 is hydrogen or alkyl; one of R5 and R6 is hydrogen and the other is alkyl-X-, phenyl-X-, alkoxy, phenyloxy, phenyl, cycloalkyl, alkyl, or phenylalkyl; or together R5 and R6 are -XCH2CH2X-; R7 is hydrogen or <IMAGE> and n is 0 or 1.
申请公布号 US4468519(A) 申请公布日期 1984.08.28
申请号 US19820388371 申请日期 1982.06.14
申请人 E. R. SQUIBB & SONS, INC. 发明人 KRAPCHO, JOHN
分类号 C07F9/564;A61K31/675;A61P9/12;C07F9/32;C07F9/572;C07F9/6561;(IPC1-7):C07F9/65;A61K31/67 主分类号 C07F9/564
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