| 发明名称 |
ANALOGIFORFARANDE FOR FRAMSTELLNING AV 4?721 EPI-ADRIAMYCIN I FORM AV DESS ALFA- RESP BETA ANOMER |
| 摘要 |
The known antitumor antibiotic adriamycin and its beta -anomer, and the novel compounds, 4'-epiadriamycin (both alpha - and beta -anomers) are prepared by condensing a novel, reactive protected derivative of adriamycinone with reactive intermediates which are 1-halo-2,3,6-trideoxy-3-trifluoroacetamido-4-trifluoroacetoxy- alpha -L-lyxo (or arabino) hexopyranoses. |
| 申请公布号 |
SE434844(B) |
申请公布日期 |
1984.08.20 |
| 申请号 |
SE19750003215 |
申请日期 |
1975.03.20 |
| 申请人 |
FARMITALIA CARLO ERBA SPA |
发明人 |
F * ARCAMONE;A * DI MARCO;S * PENCO |
| 分类号 |
C07H15/24;A61K31/70;A61K31/7028;A61K31/7034;A61K31/704;A61P35/00;C07H15/252;(IPC1-7):07H15/24 |
主分类号 |
C07H15/24 |
| 代理机构 |
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