发明名称 |
Bicyclooctane derivatives and their production and use. |
摘要 |
<p>A compound having strong anti-ulcerous or antithrombotic action which is useful in the treatment of ulcers or thrombosis has the formula:
<Chemistry id="chema01" num="0001"><Image id="ia01" he="47" wi="62" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>Wherein is a free or an esterified carboxyl gruop, or a group, of the formula.
<Chemistry id="chema02" num="0002"><Image id="ia02" he="8" wi="28" file="IMGA0002.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry><Image id="ia03" he="5" wi="83" file="IMGA0003.TIF" imgContent="character" imgFormat="TIFF" inline="no" /><Image id="ia04" he="4" wi="82" file="IMGA0004.TIF" imgContent="character" imgFormat="TIFF" inline="no" />group, a phenyl group substituted with a halogen atom or a C<Sub>1</Sub>-C<Sub>4</Sub> alkyl group, or, when taken together with the adjacent nitrogen atom to which they are attached, they represent a 5 to 7 membered saturated heterocyclic group), Y<Sup>1</Sup> is a group of the formula:
<Chemistry id="chema03" num="0003"><Image id="ia05" he="14" wi="36" file="IMGA0005.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>R<Sup>6</Sup> is a hydrogen atom or C<Sub>1</Sub>-C<Sub>4</Sub> alkyl group).
<Chemistry id="chema04" num="0004"><Image id="ia06" he="14" wi="31" file="IMGA0006.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>R<Sup>6</Sup> is a defined above).
<Chemistry id="chema05" num="0005"><Image id="ia07" he="19" wi="40" file="IMGA0007.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry><Image id="ia08" he="6" wi="79" file="IMGA0008.TIF" imgContent="character" imgFormat="TIFF" inline="no" /><Image id="ia09" he="5" wi="78" file="IMGA0009.TIF" imgContent="character" imgFormat="TIFF" inline="no" /></p> |
申请公布号 |
EP0115954(A2) |
申请公布日期 |
1984.08.15 |
申请号 |
EP19840300597 |
申请日期 |
1984.01.31 |
申请人 |
SUMITOMO CHEMICAL COMPANY, LIMITED |
发明人 |
MURAOKA, MASAMI;NAKAMURA, TOSHIO HINKO-APARTMENT HOUSE 104-GO;SUGIE, AKIHIKO;ONO, KEIICHI;YAMAMOTO, MICHIHIRO |
分类号 |
C07C69/708;A61K31/16;A61K31/19;A61K31/215;A61K31/557;A61P43/00;C07C33/14;C07C51/00;C07C59/125;C07C59/46;C07C59/62;C07C59/72;C07C67/00;C07C69/73;C07C231/00;C07C231/02;C07C231/12;C07C235/06;C07C235/16;C07C405/00;C07D307/20;C07D309/12;(IPC1-7):07C177/00;07C69/708;07C103/00;61K31/557;07C59/125 |
主分类号 |
C07C69/708 |
代理机构 |
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代理人 |
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地址 |
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