发明名称 |
Sustained release tablet containing at least 95 percent theophylline |
摘要 |
Non-disintegrating theophylline tablets having a pair of opposing substantially planar surfaces and a very thin cross-section have a high bioavailability on ingestion and a relatively steady release rate permitting a 12 hr. dosing interval for maintenance of non-toxic therapeutic blood theophylline concentrations. Excipients or tableting aids are not required, but trace amounts of a tableting lubricant are preferably included to facilitate continuous large scale production.
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申请公布号 |
US4465660(A) |
申请公布日期 |
1984.08.14 |
申请号 |
US19820451891 |
申请日期 |
1982.12.21 |
申请人 |
MEAD JOHNSON & COMPANY |
发明人 |
DAVID, STEPHEN T.;BROOKE, DANA;GALLIAN, CLAUDE E. |
分类号 |
A61K9/20;A61K31/52;(IPC1-7):A61K9/20;A61K9/22;A61K9/26 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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