ANALOGIFORFARANDE FOR FRAMSTELLNING AV 5-(2-FUROYL)-, 5-(2-TENOYL)-, 5-(3-FUROYL)- OCH 5-(3-TENOYL)-1,2 DIHYDRO-3H-PYRROLO(1,2-A)-PYRROL-1-KARBONSYRADERIVAT

摘要

Carboxylic acid esters of the formula are prepared by condensation of a compound of the formula with an amide of the formula In the formulae, X represents oxygen or sulphur, R represents hydrogen or C1-C4-alkyl, R<1> represents hydrogen, methyl, chlorine or bromine and R<2> represents C1-C4-alkyl. Hydrolysis of the carboxylic acid esters results in the corresponding carboxylic acids and their salts. The compounds are novel and exhibit an anti inflammatory, analgesic and antipyretic action. They are suitable in particular for treating inflammations, pain and febrile conditions.