| 发明名称 |
PROCESS FOR THE REMOVAL OF THE FORMYL GROUP FROM N-FORMYL PEPTIDES AND ESTERS THEREOF |
| 摘要 |
<p>A process for the removal of the formyl group in N-formylated peptides or their esters is described. The N-formyl compound is reacted with hydrazine or a substituted hydrazine of formula I: <IMAGE> at a pH between 1 and 3.5, keeping the pH constant during the reaction. The process is particularly useful for the preparation of aspartam.</p> |
| 申请公布号 |
PT74892(B) |
申请公布日期 |
1984.08.02 |
| 申请号 |
PT19820074892 |
申请日期 |
1982.05.12 |
| 申请人 |
PIERREL, S.P.A. |
发明人 |
VINCENZO GIOBBIO;GIORGIO ORNATO;LIVIO BURACCHI;ALBERTO MANGIA |
| 分类号 |
C07K1/06;C07C67/00;C07C231/00;C07C231/12;C07K1/12;C07K1/14;C07K5/075;(IPC1-7):07C103/52 |
主分类号 |
C07K1/06 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
