摘要 |
<p>Compounds of formula I <IMAGE> wherein R1 represents ethyl or vinyl, R2 represents lower alkoxy, amino, lower alkylamino which may be unsubstituted or substituted by amino, lower alkylamino, di-(lower)-alkylamino or hydroxy, di-(lower)-alkylamino or a five or six membered, saturated heterocycle which contains one or two nitrogens as heteroatoms and which may be unsubstituted or substituted by lower alkyl and R3 and R4 represent, independently, hydrogen or lower alkyl, in free base o; acid addition or quaternary salt form, exhibit pharmacological activity, particularly against bacteria and obligatory anaerobes, and can be incorporated into chemotherapeutic compositions.</p> |