| 摘要 |
A process for the preparation of alpha -L-aspartyl-L-phenylalanine alkyl esters, and namely of the methyl ester or aspartame, characterized by using, as starting material, a L-asparagine derivative having the amino group protected, which is reacted with an alkyl ester of L-phenylalanine to produce a dipeptide whose amido group is subsequently converted to carboxylic group by means of nitrite ions. |
