发明名称 PROCEDIMIENTO PARA LA PREPARACION DE FORMAS 5Z DE DERIVADOS DE 2,3,4-TRINOR-1,5-INTER-M-FENILEN-PROSTACICLINA
摘要 <p>of the Invention The invention relates to the preparation of the 5Z-isomers of 2,3,4-trinor-1,5-inter-m-phenylene-prostacyclin derivatives of the formula < IMG > (I) wherein R1 is a hydrogen atom, a cation or a lower alkyl radical, R2 is hydrogen or methyl, A is a member of the group consisting of the radicals -CH2-CH2-, (trans)-CH=CH- and -C?C- and B is an alkyl radical or a cycloalkyl radical optionally substituted by a lower alkyl radical by isomerization of a compound of the formula < IMG > (IIE) wherein R2, A and B have the same meaning as above and R? is a lower alkyl or aralkyl radical,</p>
申请公布号 ES522674(D0) 申请公布日期 1984.08.01
申请号 ES19740005226 申请日期 1983.05.24
申请人 GRUNENTHAL GMBH. 发明人
分类号 A61K31/23;A61K31/34;C07D;C07D307/93;C07D307/935;C07D307/937;(IPC1-7):C07D307/93 主分类号 A61K31/23
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