| 发明名称 |
Carboxyalkyl amino acid derivatives of various substituted prolines |
| 摘要 |
Carboxyalkyl dipeptides of the formula <IMAGE> wherein R4 is a 3-, 4-, 5-, or 4,4-substituted proline are disclosed. These compounds are useful as hypotensive agents due to their angiotensin converting enzyme inhibition activity.
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| 申请公布号 |
US4462943(A) |
申请公布日期 |
1984.07.31 |
| 申请号 |
US19810306553 |
申请日期 |
1981.09.28 |
| 申请人 |
E. R. SQUIBB & SONS, INC. |
发明人 |
PETRILLO, JR., EDWARD W.;GORDON, ERIC M.;KRAPCHO, JOHN;SPRAGUE, PETER W. |
| 分类号 |
A61K38/00;C07K5/02;(IPC1-7):C07C103/52;A61K37/00;A61K31/40 |
主分类号 |
A61K38/00 |
| 代理机构 |
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