发明名称 Bis-esters of dicarboxylic acids with amoxicillin and certain hydroxymethylpenicillanate 1,1-dioxides
摘要 Antibacterial bis-esters of 1,4-cyclohexanedicarboxylic acids and alkane dicarboxylic acids wherein the ester moieties are derived from different alcohols; one alcohol being hydroxymethylpenicillanate 1,1-dioxide, or the 6-beta-hydroxymethyl or the 6-alpha-aminomethyl derivative thereof; and the other being 6-[D-(2-amino-2-(p-hydroxyphenyl)acetamido)]penicillanic acid (amoxicillin); and pharmaceutically acceptable salts thereof; a method for the use of said esters and their salts, and methods for their preparation.
申请公布号 US4462934(A) 申请公布日期 1984.07.31
申请号 US19830481108 申请日期 1983.03.31
申请人 PFIZER INC. 发明人 JASYS, VYTAUTAS J.
分类号 C07D519/06;A61K31/43;A61P31/04;C07D499/00;C07D499/32;C07D499/68;C07D499/86;C07D499/861;C07D499/87;C07D499/897;C07D519/00;(IPC1-7):C07D499/48 主分类号 C07D519/06
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