发明名称 A POLYCISTRONIC EXPRESSION VECTOR FOR VERTEBRATE CELLS
摘要 An expression vector capable of expressing in a vertebrate host cell culture a desired protein and a secondary protein, which vector comprises a DNA sequence encoding for a desired protein and a DNA sequence encoding for a secondary protein wherein both said DNA sequences are operably linked to the same promoter sequence and separated by translational stop and start codons. …<??>The secondary sequence provides for a convenient screening marker, both for transformants in general, and for transformants showing high expression levels for the primary sequence, as well as serving as a control device whereby the expression of a desired polypeptide can be regulated, most frequently enhanced.
申请公布号 AU2353184(A) 申请公布日期 1984.07.26
申请号 AU19840023531 申请日期 1984.01.17
申请人 GENENTECH INC. 发明人 ARTHUR DAVID LEVINSON;CHRISTIAN CLINTON SIMONSEN
分类号 C12N5/10;C07H21/04;C07K14/00;C07K14/02;C12N5/00;C12N15/00;C12N15/09;C12N15/67;C12N15/85;C12P21/00;C12Q1/04;C12R1/91 主分类号 C12N5/10
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