发明名称 |
NAPHTHOXYALKYLAMINES AND RELATED COMPOUNDS AS ANTIINFLAMMATORY AGENTS |
摘要 |
Compounds of the formula: <CHEM> >and the pharmaceutically acceptable acid addition salts thereof, wherein; Y is halo, alkoxy or alkyl; a is 0 or 1; b is an integer from 2-12 with the proviso that if b is 2 or 3, a cannot be 0; and X is selected from <CHEM> in which each R<1> is independently alkyl or phenyl or in -NHR2<1>, both R<1> together are alkylene; and R<2> is cycloalkyl or phenyl; have antiinflammatory properties and are useful in the treatment of conditions characterized by inflammation and swelling. |
申请公布号 |
ZA8209151(B) |
申请公布日期 |
1984.07.25 |
申请号 |
ZA19820009151 |
申请日期 |
1982.12.13 |
申请人 |
SYNTEX INC |
发明人 |
NELSON PETER HAROLD;RINGOLD HOWARD JOSEPH;UNGER STEFAN HOWARD;THIEME THOMAS R |
分类号 |
A61K31/13;A61K31/135;A61K31/17;A61K38/28;A61P29/00;C07C41/00;C07C43/20;C07C43/225;C07C43/23;C07C67/00;C07C213/00;C07C217/18;C07C239/00;C07C275/26;C07C275/30;C07D295/092 |
主分类号 |
A61K31/13 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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