发明名称 |
Desulfurization of penicillins to prepare azetidinones |
摘要 |
A process for the Raney nickel desulfurization of penicillins is described. In the process of the invention, amino penicillanic acid or derivatives thereof are reacted with Raney nickel under controlled conditions of temperature and time to yield azetidinones which are useful as intermediates for the synthesis of monocyclic beta-lactam antibiotics.
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申请公布号 |
US4461726(A) |
申请公布日期 |
1984.07.24 |
申请号 |
US19820379386 |
申请日期 |
1982.05.17 |
申请人 |
HOFFMANN-LA ROCHE INC. |
发明人 |
WEI, CHUNG-CHEN;WEIGELE, MANFRED |
分类号 |
B01J25/02;C07D205/085;(IPC1-7):C07D205/08;C07D403/04;C07D401/12;C07D403/12 |
主分类号 |
B01J25/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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