| 摘要 |
<p>A device for the transdermal administration of a drug to a patient comprising a reservoir (11) for the drug to be administered, for example nitroglycerin in an ointment carrier, and means associated with the reservoir (11) for ensuring a supply of the drug to the skin at a pre-determined rate. The latter means in the case of a drug in an ointment carrier suitably consists of a plate (13) movable in piston-like fashion within the reservoir (11) by application of external pressure thereto, resulting in a constant egress of ointment from the device (10) to the skin through a microporous, drug transfer membrane (15,16). The means for applying external pressure is suitably a leaf spring (24) having a face (25) which engages the movable plate (13). Means (19, 20) are provided for attaching the reservoir (11) to a support member (21), the support member (21), in use, is readily detachable from that portion of the body to which the device (10) is applied by means of the strap (22).</p> |
