| 摘要 |
<p>Process for the preparation of a furan derivative The invention relates to a process for the preparation of ranitidine of formula (I) (I) which comprises reacting a thiol of formula (II) (II) with an alkylating agent of formula (III) (III) where L is a leaving group, preferably halogen. The invention also relates to novel intermediates, the thiol of formula (II) (II) in the form of a stable acid addition salt, and the isothiourea of formula (IV) (IV) and stable acid addition salts thereof.</p> |
