Soluble liver uricase with a process for the preparation thereof and with the use thereof

摘要

The present invention provides liver uricase, wherein it is covalently bond to a water-soluble polysaccharide, polyacid anhydride, polyvinylpyrrolidone or acid anhydride as carrier substance and is still soluble at pH values below 6. The present invention also provides a process for the preparation of this liver uricase.