| 发明名称 |
8,10-Dideazaminopterins |
| 摘要 |
8,10-Dideazaminopterins of the formula <IMAGE> where R is hydrogen or alkyl of 1 to about 8 carbon atoms and their carboxylate and acid addition salts are described. These compounds exhibit antineoplastic activity that is similar to but more effective than methotrexate.
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| 申请公布号 |
US4460591(A) |
申请公布日期 |
1984.07.17 |
| 申请号 |
US19820411658 |
申请日期 |
1982.08.26 |
| 申请人 |
SRI INTERNATIONAL |
发明人 |
DEGRAW, JOSEPH I.;KELLY, LAWRENCE F.;SIROTNAK, FRANCIS M. |
| 分类号 |
C07D471/04;(IPC1-7):C07D471/04;C07D487/04;A61K31/50 |
主分类号 |
C07D471/04 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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